US 12,188,934 B2
Signatures and determinants for diagnosing infections and methods of use thereof
Kfir Oved, Hof HaCarmel (IL); Eran Eden, Haifa (IL); and Ilan Ifergan, Haifa (IL)
Assigned to MeMed Diagnostics Ltd., Tirat HaCarmel (IL)
Filed by MeMed Diagnostics Ltd., Tirat HaCarmel (IL)
Filed on Oct. 22, 2021, as Appl. No. 17/507,994.
Application 16/687,726 is a division of application No. 15/237,728, filed on Aug. 16, 2016, granted, now 10,502,739, issued on Dec. 10, 2019.
Application 15/237,728 is a division of application No. 14/377,887, granted, now 9,726,668, issued on Aug. 8, 2017, previously published as PCT/EP2013/052619, filed on Feb. 8, 2013.
Application 17/507,994 is a continuation of application No. 16/687,726, filed on Nov. 19, 2019, granted, now 11,175,291.
Claims priority of provisional application 61/652,631, filed on May 29, 2012.
Claims priority of provisional application 61/596,950, filed on Feb. 9, 2012.
Prior Publication US 2022/0042994 A1, Feb. 10, 2022
Int. Cl. G01N 33/00 (2006.01); G01N 27/447 (2006.01); G01N 33/569 (2006.01); G01N 33/68 (2006.01)
CPC G01N 33/56983 (2013.01) [G01N 27/447 (2013.01); G01N 27/44726 (2013.01); G01N 27/44739 (2013.01); G01N 33/56911 (2013.01); G01N 33/6863 (2013.01); G01N 33/6866 (2013.01); G01N 2333/70575 (2013.01); G01N 2800/52 (2013.01)] 8 Claims
 
1. A kit comprising antibodies, at least one of said antibodies is a monoclonal antibody, wherein a first antibody of said antibodies specifically binds to TNF-related apoptosis-inducing ligand (TRAIL) protein, a second antibody of said antibodies specifically binds to Procalcitonin (PCT) protein, and a third antibody of said antibodies specifically binds to C-Reactive protein (CRP), wherein the kit does not comprise more than three additional antibodies which specifically bind to additional determinants, each of said three additional antibodies targeting a different soluble determinant of said additional determinants, wherein said determinant is a protein whose level is differentially expressed in a viral and bacterial infection.