US 12,188,924 B2
Methods and systems for analyte detection and analysis
Kristopher Barbee, Pleasanton, CA (US); Nathan Beckett, Oakland, CA (US); Denis Pristinski, Dublin, CA (US); Derek Schulte, Los Angeles, CA (US); Avishai Bartov, Hod-Hasharon (IL); Jamie Sullivan, Eugene, OR (US); Dumitru Brinza, Montara, CA (US); Abizar Lakdawalla, Los Altos Hills, CA (US); Steven Menchen, Fremont, CA (US); Gilad Almogy, Palo Alto, CA (US); and Mark Pratt, Bozeman, MT (US)
Assigned to Ultima Genomics, Inc., Fremont, CA (US)
Filed by Ultima Genomics, Inc., Newark, CA (US)
Filed on Jul. 20, 2023, as Appl. No. 18/224,378.
Application 18/224,378 is a continuation of application No. 17/962,163, filed on Oct. 7, 2022, granted, now 11,747,323.
Application 17/962,163 is a continuation of application No. 16/862,196, filed on Apr. 29, 2020, granted, now 11,499,962, issued on Nov. 15, 2022.
Application 16/862,196 is a continuation of application No. PCT/US2018/061598, filed on Nov. 16, 2018.
Application 16/862,196 is a continuation of application No. 15/974,441, filed on May 8, 2018, granted, now 10,267,790, issued on Apr. 23, 2019.
Application 16/862,196 is a continuation of application No. 15/974,364, filed on May 8, 2018, granted, now 10,344,328, issued on Jul. 9, 2019.
Application 16/862,196 is a continuation of application No. 15/974,543, filed on May 8, 2018, granted, now 10,273,528, issued on Apr. 30, 2019.
Claims priority of provisional application 62/623,743, filed on Jan. 30, 2018.
Claims priority of provisional application 62/664,049, filed on Apr. 27, 2018.
Claims priority of provisional application 62/588,139, filed on Nov. 17, 2017.
Prior Publication US 2024/0027425 A1, Jan. 25, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 33/49 (2006.01); G01N 1/02 (2006.01); G01Q 10/04 (2010.01); G01N 1/22 (2006.01)
CPC G01N 33/492 (2013.01) [G01N 1/02 (2013.01); G01Q 10/04 (2013.01); G01N 2001/2291 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A method for processing a biological analyte, comprising:
(a) providing a substrate at a first processing station, wherein the substrate comprises a plurality of biological analytes immobilized thereto, wherein the plurality of biological analytes comprises the biological analyte;
(b) using a moving arm, moving the substrate from the first processing station to a second processing station, wherein the first processing station and the second processing station are located at different locations;
(c) at the second processing station, dispensing a first solution to the substrate, via a first fluid outlet port not in contact with the substrate, to contact the plurality of biological analytes with the first solution, wherein the first solution comprises a plurality of probes; and
(d) detecting one or more signals or signal changes, or lack thereof, from the substrate to process the biological analyte.