US 12,188,911 B2
Chromatography system
Jens Widehammar, Uppsala (SE); Key Hyckenberg, Uppsala (SE); Örjan Grelsson, Uppsala (SE); Lars Mattsson, Uppsala (SE); and Kjell Karlsson, Uppsala (SE)
Assigned to CYTIVA SWEDEN AB, Uppsala (SE)
Appl. No. 17/602,701
Filed by CYTIVA SWEDEN AB, Uppsala (SE)
PCT Filed Apr. 16, 2020, PCT No. PCT/EP2020/060651
§ 371(c)(1), (2) Date Oct. 8, 2021,
PCT Pub. No. WO2020/216666, PCT Pub. Date Oct. 29, 2020.
Claims priority of application No. 1905886 (GB), filed on Apr. 26, 2019.
Prior Publication US 2022/0163493 A1, May 26, 2022
Int. Cl. G01N 30/86 (2006.01); B01D 15/20 (2006.01); G01N 30/02 (2006.01); G01N 30/46 (2006.01)
CPC G01N 30/8658 (2013.01) [B01D 15/206 (2013.01); G01N 30/46 (2013.01); G01N 30/86 (2013.01); G01N 30/8631 (2013.01); G01N 30/8651 (2013.01); G01N 2030/027 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A chromatography system configured to:
perform chromatography column efficiency testing for a specific column to determine one or more efficiency parameters,
provide guidance to a user with respect to column efficiency,
wherein the system has a controller configured to access data to calculate a column compression plate height (h) and a peak asymmetry factor (As), said data being derived from at least one or more stored parameters of the specific column and a resin to be used in the column, and
wherein the system is configured to determine if the specific column is suitable for use or is not suitable for use based on the column compression plate height.