US 12,188,874 B2
Chemiluminescence detector and detection method thereof
Wei Rao, Guangdong (CN); Li Yin, Guangdong (CN); Liang Zhu, Guangdong (CN); Junhui Tang, Guangdong (CN); and Yi Hu, Guangdong (CN)
Assigned to Shenzhen New Industries Biomedical Engineering Co., Ltd., Guangdong (CN)
Filed by Shenzhen New Industries Biomedical Engineering Co., Ltd., Guangdong (CN)
Filed on Dec. 7, 2018, as Appl. No. 16/212,714.
Claims priority of application No. 201711465127.0 (CN), filed on Dec. 28, 2017.
Prior Publication US 2019/0204233 A1, Jul. 4, 2019
Int. Cl. G01N 21/76 (2006.01); G01N 21/25 (2006.01); G01N 21/64 (2006.01); G01N 35/02 (2006.01); G01N 35/04 (2006.01)
CPC G01N 21/76 (2013.01) [G01N 21/253 (2013.01); G01N 21/6428 (2013.01); G01N 21/6452 (2013.01); G01N 35/025 (2013.01); G01N 2035/0439 (2013.01)] 15 Claims
OG exemplary drawing
 
1. A chemiluminescence detector, wherein the chemiluminescence detector comprises:
a reagent storage device, configured to store a reagent;
a reaction device, configured to support a plurality of support reaction containers and perform a sample adding operation, a reagent adding operation and an incubating operation, the reaction device comprising a reaction outer disc mechanism configured to support the reaction containers and perform the reagent adding operation and an uniform mixing operation and a reaction inner disc mechanism configured to support the reaction containers and perform the incubating operation, the reaction outer disc mechanism being arranged outside the reaction inner disc mechanism in a sleeving manner, the reaction outer disc mechanism and the reaction inner disc mechanism being respectively and independently operated and the reaction outer disc mechanism and the reaction inner disc mechanism being arranged coaxially, the reaction device further comprises a buffer disc mechanism; and the buffer disc mechanism is provided independent of the reaction outer disc mechanism and is located at the outer periphery side of the reaction outer disc mechanism;
a reaction container automatic transmission device, configured to transmit the reaction containers, the reaction container automatic transmission device is located at the outer periphery side of the buffer disc mechanism,
a new cup grabbing mechanism; and the new cup grabbing mechanism is arranged corresponding to the reaction container automatic transmission device and the reaction device, and is configured to transfer each of the reaction containers in the reaction container automatic transmission device to the buffer disc mechanism;
a separate injection device, configured to respectively transfer a sample and the reagent to the reaction containers, the separate injection device comprises a sample adding mechanism and a plurality of liquid transfer mechanisms; the sample adding mechanism is located at an outer periphery side of the buffer disc mechanism and is configured to transfer the sample to empty reaction containers of the buffer disc mechanism; the liquid transfer mechanisms are arranged corresponding to the reaction outer disc mechanism and reagent storage mechanisms of the reagent storage device; and the liquid transfer mechanisms transfer the reagent in the reagent storage mechanisms to the reaction containers of the reaction outer disc mechanism, the buffer disc mechanism comprises a buffer supporting plate for supporting the reaction containers and a buffer driving structure for driving the buffer supporting plate to rotate, the reaction outer disc mechanism comprises a reaction outer disc supporting plate capable of being rotated, a reaction outer disc mounting structure and a reaction outer disc driving structure, the reaction outer disc supporting plate is able to accommodate the reaction containers, the reaction outer disc driving structure is connected with the reaction outer disc supporting plate, and drives the reaction outer disc supporting plate to rotate relative to the reaction outer disc mounting structure;
a cleaning device, configured to remove impurities in the reaction containers, and
a measuring device, configured to detect a to-be-tested substance in the reaction containers;
a sample conveying device configured to convey the sample to a sample suction position, wherein the sample suction position is arranged at a periphery side of the buffer disc mechanism and corresponding to the sample adding mechanism; and the sample adding mechanism sucks up the sample at the sample suction position and transfers the sample to the empty reaction containers of the buffer disc mechanism, the sample conveying device comprises a sample storage mechanism and a sample conveying mechanism detachably connected with the sample storage mechanism; multiple sample racks loaded with the sample are stored in the sample storage mechanism; the sample storage mechanism transfers each of the sample racks to the sample conveying mechanism; and the each of the sample racks is conveyed by the sample conveying mechanism to the sample suction position, the sample conveying device further comprises a sample transfer mechanism, through sample transfer mechanism, the sample racks in the sample storage mechanism is transferred to the sample conveying mechanism;
a cleaning cup grabbing mechanism, the cleaning cup grabbing mechanism is arranged corresponding to the cleaning device and the reaction outer disc mechanism, and is configured to transfer each of the reaction containers among the reaction outer disc mechanism, the reaction inner disc mechanism and the cleaning device, wherein the cleaning cup grabbing mechanism is able to transfer incubated reaction containers in the reaction inner disc mechanism to the cleaning device, the cleaning cup grabbing mechanism further is able to transfer the reaction containers that are cleaned and need to be added with the reagent again to the reaction outer disc mechanism;
wherein the reagent storage device, the separate injection device, the cleaning device and the measuring device are arranged around an outer periphery side of the reaction outer disc mechanism.