US 12,188,003 B1
Methods and systems for performing biochemical processes
Gergo Bohner, Cambridge (GB); Adam Luke Hiles, Leighton Buzzard (GB); Samuel Isidor Jones, London (GB); Kevin Lynagh, Tacoma, WA (US); Ryan Olf, Cambridge (GB); Gabor Pap, Stevenage (GB); Spencer Ryan Wilson, London (GB); and Thomas Felix Martin Cummings, London (GB)
Assigned to Trisk Bio Ltd., Stevenage (GB)
Filed by Trisk Bio Ltd., Stevenage (GB)
Filed on Sep. 28, 2023, as Appl. No. 18/374,098.
Int. Cl. C12M 1/00 (2006.01); C12M 1/34 (2006.01)
CPC C12M 47/12 (2013.01) [C12M 23/40 (2013.01); C12M 29/04 (2013.01); C12M 41/00 (2013.01)] 5 Claims
OG exemplary drawing
 
1. A system for processing a liquid sample, the system comprising a first component and a second component, the second component being distinct from the first component and reversibly connected to the first component, wherein:
the first component comprises:
an interface side, the interface side comprising at least 4 orifices, wherein the at least 4 orifices comprise a first orifice, a second orifice, a third orifice, and a fourth orifice;
a first pressure actuator;
at least 2 sample containers, wherein the at least 2 sample containers comprise a first sample container and a second sample container;
a first gas conduit, the first gas conduit connecting the first sample container to the first pressure actuator and configured to transmit pressure from the first pressure actuator to the first sample container and impel a sample out of the first sample container;
at least 4 connectors, wherein the at least 4 connectors comprise a first connector, a second connector, a third connector, and a fourth connector;
at least 2 sample conduits, wherein the at least 2 sample conduits comprise a first sample conduit and a second sample conduit;
and
a reagent conduit;
wherein:
the first sample conduit is connected to the first sample container and the first connector,
the second sample conduit is connected to the second sample container and the second connector;
the reagent conduit is connected to the third and fourth connectors; and
the first, second, third, and fourth connectors are disposed in the first, second, third, and fourth orifices, respectively;
the second component comprises:
a connector manifold, the connector manifold comprising at least 4 connectors, wherein the at least 4 connectors comprise a fifth connector, a sixth connector, a seventh connector, and an eighth connector;
a fractionation moiety, the fractionation moiety being reversibly connected to the fifth, sixth, and seventh connectors and configured to perform a biochemical fractionation procedure; and
a reagent container reversibly connected to the eighth connector;
the first connector is reversibly connected to the fifth connector;
the second connector is reversibly connected to the sixth connector;
the third connector is reversibly connected to the seventh connector; and
the fourth connector is reversibly connected to the eighth connector.