US 12,187,716 B2
TYK2 kinase inhibitors
John Charles Reader, Cambridgeshire (GB)
Assigned to SAREUM LIMITED, Cambridgeshire (GB)
Appl. No. 17/283,151
Filed by SAREUM LIMITED, Cambridgeshire (GB)
PCT Filed Oct. 7, 2019, PCT No. PCT/EP2019/077118
§ 371(c)(1), (2) Date Apr. 6, 2021,
PCT Pub. No. WO2020/074461, PCT Pub. Date Apr. 16, 2020.
Claims priority of application No. 1816369 (GB), filed on Oct. 8, 2018.
Prior Publication US 2021/0387981 A1, Dec. 16, 2021
Int. Cl. C07D 417/12 (2006.01)
CPC C07D 417/12 (2013.01) 20 Claims
 
1. A compound having the formula (1):

OG Complex Work Unit Chemistry
or being a salt or tautomer thereof; wherein R1 is hydrogen or fluorine.