US 12,186,752 B2
Microfluidic device including at least one microfluidic structure and analysis method of sample supplied thereto
Tae Seok Seo, Suwon-si (KR); Van Hiep Nguyen, Suwon (KR); and Minh Vu Phan, Suwon (KR)
Filed by UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY, Yongin-si (KR)
Filed on Jun. 26, 2021, as Appl. No. 17/359,505.
Claims priority of application No. 10-2020-0052667 (KR), filed on Apr. 29, 2020; application No. 10-2020-0052668 (KR), filed on Apr. 29, 2020; and application No. 10-2020-0052669 (KR), filed on Apr. 29, 2020.
Prior Publication US 2021/0339251 A1, Nov. 4, 2021
Int. Cl. B01L 3/00 (2006.01)
CPC B01L 3/502761 (2013.01) [B01L 2300/0681 (2013.01); B01L 2300/0883 (2013.01)] 17 Claims
OG exemplary drawing
 
1. A microfluidic device comprising: a rotating body;
at least two microfluidic structures disposed at a predetermined interval in the rotating body;
a solution inlet; and
a sharing channel connected between the solution inlet and each of the at least two microfluidic structures,
wherein each of the at least two microfluidic structures comprises;
a pretreatment unit which shares a solution injected through the solution inlet and the sharing channel and performs a pretreating process for a sample injected through a sample inlet and the solution;
a storage unit which is located outside the pretreatment unit in a radial direction in the rotating body and separately stores the sample and solution pretreated by the pretreatment unit based on a rotational direction of the rotating body;
and a detection unit which distributes a target material in the pretreated sample from the storage unit and performs the detection on the distributed target material,
wherein the pretreatment unit comprises:
a sample chamber for receiving the sample injected through the sample inlet;
a solution chamber for receiving, via the sharing channel, the solution injected through the solution inlet;
a capture filter for capturing a target material from the injected sample; and
a solution valve disposed between the solution chamber and the capture filter and configured to control a flow from the solution chamber to the capture filter such that the solution in the solution chamber is configured to not be moved to the capture filter until the solution is shared in each solution chamber of a different one of the least two microfluidic structures.