US 12,186,743 B2
Reagent manifold with in-line filter
Nicholas Everette Watkins, Sacramento, CA (US); Garrick Anthony Maurer, Roseville, CA (US); Richard Milson, Citrus Heights, CA (US); Frederick Rupisan Cuenco, Antelope, CA (US); and Christopher Dallas Griner, Sacramento, CA (US)
Assigned to Beckman Coulter, Inc., Brea, CA (US)
Filed by Beckman Coulter, Inc., Brea, CA (US)
Filed on Sep. 10, 2021, as Appl. No. 17/471,945.
Application 17/471,945 is a continuation of application No. PCT/US2020/022008, filed on Mar. 11, 2020.
Claims priority of provisional application 62/818,461, filed on Mar. 14, 2019.
Prior Publication US 2022/0008910 A1, Jan. 13, 2022
Int. Cl. B01L 3/02 (2006.01)
CPC B01L 3/0293 (2013.01) [B01L 2200/026 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/16 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/123 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A manifold system adapted for use in a sample testing instrument, the manifold system comprising:
(a) a manifold comprising:
(i) an air inlet channel and a reagent outlet channel,
(ii) a bottle receiver adapted to couple a bottle of reagent with the air intake channel and the reagent outlet channel when the bottle is placed in the bottle receiver,
(iii) the air intake channel comprising an air channel bore, the air intake channel adapted to allow the flow of air from a connected air source to the bottle, and
(iv) the reagent outlet channel comprising a reagent channel bore, the reagent outlet channel adapted to allow the flow of reagent from the bottle to a reagent distributor assembly of the sample testing instrument,
(b) an air gasket removably disposed within the air channel bore, wherein the air gasket is adapted to seal and control the flow of air to the bottle;
(c) a reagent gasket removably disposed within the reagent channel bore, wherein the reagent gasket is adapted to seal and control the flow of reagent from the bottle; and
(d) a filter removably disposed within the reagent channel bore between the reagent gasket and the reagent distributor assembly and adapted to prevent particulate from passing through the reagent outlet channel towards the reagent distributor assembly.