US 12,186,709 B2
Three-compartment bipolar membrane electrodialysis of salts of amino acids
Eduardo Aurelio Casanova, St. Louis, MO (US); Justin Robert Struble, St. Louis, MO (US); and Jian Xu, St. Louis, MO (US)
Assigned to Monsanto Technology LLC, Saint Louis, MO (US)
Appl. No. 16/972,328
Filed by Monsanto Technology LLC, St. Louis, MO (US)
PCT Filed Jun. 6, 2019, PCT No. PCT/US2019/035749
§ 371(c)(1), (2) Date Dec. 4, 2020,
PCT Pub. No. WO2019/236814, PCT Pub. Date Dec. 12, 2019.
Claims priority of provisional application 62/681,205, filed on Jun. 6, 2018.
Prior Publication US 2021/0229040 A1, Jul. 29, 2021
Int. Cl. B01D 61/44 (2006.01); B01D 61/46 (2006.01); B01D 61/54 (2006.01); C07C 227/18 (2006.01); C07C 227/40 (2006.01); C07F 9/38 (2006.01)
CPC B01D 61/445 (2013.01) [B01D 61/46 (2013.01); B01D 61/54 (2013.01); C07C 227/18 (2013.01); C07C 227/40 (2013.01); C07F 9/3813 (2013.01); B01D 2311/12 (2013.01); B01D 2311/18 (2013.01)] 29 Claims
OG exemplary drawing
 
1. A process for preparing an amino acid, the process comprising:
introducing an aqueous electrolyte comprising a first acid into an acid compartment of a three-compartment electrodialysis bipolar membrane cell comprising an acid compartment, a salt compartment, and a base compartment;
introducing a feed salt stream comprising a salt of the amino acid into the salt compartment of the three-compartment bipolar membrane cell, wherein the salt of the amino acid is formed by reacting an amino acid with a base; and
introducing an aqueous stream into the base compartment of the three-compartment bipolar membrane cell;
wherein the first acid and the amino acid are different, and the amino acid has a pKa greater than 2.0 and the first acid introduced into the acid compartment of the three-compartment bipolar membrane cell has a pKa less than the pKa of the amino acid, and wherein:
the three-compartment bipolar membrane cell further comprises a cathode and an anode, the process further comprising applying an electric potential between the cathode and the anode.