US 12,186,553 B2
Electrical stimulation for cancer treatment with internal and external electrodes
Brian L. Schmidt, White Bear Lake, MN (US); Devon N. Arnholt, Shoreview, MN (US); Benjamin Keith Stein, Shoreview, MN (US); Keith R. Maile, New Brighton, MN (US); William J. Linder, Golden Valley, MN (US); Ron A. Balczewski, Bloomington, MN (US); Jacob M. Ludwig, Isanti, MN (US); and Aleksandra Kharam, Maple Grove, MN (US)
Assigned to Boston Scientific Scimed, Inc., Maple Grove, MN (US)
Filed by Boston Scientific Scimed, Inc., Maple Grove, MN (US)
Filed on Mar. 20, 2023, as Appl. No. 18/123,776.
Application 18/123,776 is a continuation of application No. 16/855,421, filed on Apr. 22, 2020, granted, now 11,607,542.
Claims priority of provisional application 62/837,401, filed on Apr. 23, 2019.
Prior Publication US 2023/0330416 A1, Oct. 19, 2023
Int. Cl. A61N 1/36 (2006.01); A61N 1/04 (2006.01); A61N 1/05 (2006.01); A61N 1/378 (2006.01)
CPC A61N 1/36002 (2017.08) [A61N 1/0408 (2013.01); A61N 1/05 (2013.01); A61N 1/36017 (2013.01); A61N 1/36034 (2017.08); A61N 1/3787 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A medical device system comprising:
at least one electric field generating circuit configured to generate two or more electric fields; and
control circuitry in communication with the electric field generating circuit, the control circuitry configured to control delivery of the two or more electric fields from the at least one electric field generating circuit; and
four or more electrodes to deliver the electric fields to the site of a cancerous tumor within a patient, wherein at least two electrodes are configured to be non-implanted, and wherein at least two electrodes are configured to be implanted;
wherein the control circuitry causes the electric field generating circuit to generate two or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz; and
an implantable sensor in signal communication with the control circuitry; and
wherein the electric fields are delivered across at least two vectors, wherein each vector includes both an electrode configured to be implanted and an electrode configured to be non-implanted.