US 12,186,516 B2
Method and device for producing microneedles
Michael Kulik, Urmitz (DE); and Andreas Hennig, Messstetten (DE)
Assigned to LTS Lohmann Therapie-Systeme AG, Andernach (DE)
Appl. No. 17/312,504
Filed by LTS Lohmann Therapie-Systeme AG, Andernach (DE)
PCT Filed Dec. 4, 2019, PCT No. PCT/EP2019/083717
§ 371(c)(1), (2) Date Jun. 10, 2021,
PCT Pub. No. WO2020/120262, PCT Pub. Date Jun. 18, 2020.
Claims priority of application No. 102018009594.1 (DE), filed on Dec. 11, 2018.
Prior Publication US 2022/0062604 A1, Mar. 3, 2022
Int. Cl. A61M 37/00 (2006.01); B29C 39/02 (2006.01); B29C 39/24 (2006.01); B29C 39/26 (2006.01); B29L 31/00 (2006.01)
CPC A61M 37/0015 (2013.01) [B29C 39/026 (2013.01); B29C 39/24 (2013.01); B29C 39/26 (2013.01); A61M 2037/0046 (2013.01); A61M 2037/0053 (2013.01); B29L 2031/7544 (2013.01)] 10 Claims
OG exemplary drawing
 
1. A method for producing microneedle arrays in a mold comprising:
providing a mold comprising a plurality of receptacles that taper from an upper base surface to a lower tip surface; and
feeding a first component through the tip surfaces, or through a receptacle inner shell surface, into at least two receptacles through a feed opening that is spaced apart from the base surface,
wherein the at least two receptacles are filled with an additional component from above the feed opening, wherein the fillings of at least the two receptacles are formed of at least the first component and the additional component, wherein the fillings of at least the two receptacles are connected to one another above the base surfaces, and wherein, after the first component and the additional component have solidified, the microneedle array comprising the fillings that have solidified to form needles is removed from the mold.