US 12,186,515 B2
Microneedle assembly
Young Shin Kim, Cincinnati, OH (US); and Camilo Cano, Union, KY (US)
Assigned to Ticona LLC, Florence, KY (US)
Filed by Ticona LLC, Florence, KY (US)
Filed on Apr. 21, 2021, as Appl. No. 17/235,982.
Claims priority of provisional application 63/069,891, filed on Aug. 25, 2020.
Claims priority of provisional application 63/034,429, filed on Jun. 4, 2020.
Claims priority of provisional application 63/016,560, filed on Apr. 28, 2020.
Prior Publication US 2021/0330952 A1, Oct. 28, 2021
Int. Cl. A61M 37/00 (2006.01); A61B 5/145 (2006.01); A61K 39/215 (2006.01); C08K 3/34 (2006.01); C08L 27/18 (2006.01); C09K 19/38 (2006.01); G01N 33/49 (2006.01); A61K 39/00 (2006.01); B82Y 5/00 (2011.01); B82Y 30/00 (2011.01); B82Y 35/00 (2011.01)
CPC A61M 37/0015 (2013.01) [A61B 5/14532 (2013.01); A61K 39/215 (2013.01); C08K 3/346 (2013.01); C08L 27/18 (2013.01); C09K 19/3838 (2013.01); G01N 33/49 (2013.01); A61K 39/00 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0061 (2013.01); A61M 2202/30 (2013.01); B82Y 5/00 (2013.01); B82Y 30/00 (2013.01); B82Y 35/00 (2013.01)] 53 Claims
OG exemplary drawing
 
1. A microneedle assembly comprising an array of microneedles being arranged in at least one predetermined geometric pattern on a support, wherein the microneedles contain a base that includes a lower portion positioned in proximity to the support and an opposing upper portion extending from the lower portion in a longitudinal direction, wherein a tip extends from the upper portion of the base in the longitudinal direction and terminates at an edge, the tip, the base, or a combination thereof include a polymer composition containing a liquid crystalline polymer, and wherein a centerline extends through the base in the longitudinal direction, and further wherein the microneedles exhibit an offset factor, k, of about 20 or less as determined according to the following equation:
k=O/((L1+L2)/D)
wherein,
O is a distance that the edge of the tip is offset from the centerline in a lateral direction perpendicular to the longitudinal direction;
L1 is a length of the tip;
L2 is a length of the base; and
D is a width of the base.