US 12,186,449 B2
Dermal fillers and applications thereof
Oded Shoseyov, Shoham (IL); Nadav Orr, Mazkeret Batya (IL); Jasmine Seror Maknouz, Tel-Aviv (IL); and Revital Zarka, Mazkeret Batya (IL)
Assigned to CollPlant Ltd., Rehovot (IL)
Filed by CollPlant Ltd., Rehovot (IL)
Filed on Oct. 12, 2023, as Appl. No. 18/379,190.
Application 18/379,190 is a division of application No. 17/052,216, granted, now 11,801,329, previously published as PCT/IL2019/050492, filed on May 2, 2019.
Claims priority of provisional application 62/666,267, filed on May 3, 2018.
Prior Publication US 2024/0042099 A1, Feb. 8, 2024
Int. Cl. A61L 27/26 (2006.01); A61K 8/04 (2006.01); A61K 8/65 (2006.01); A61K 8/73 (2006.01); A61L 27/36 (2006.01); A61Q 19/08 (2006.01); C08L 5/08 (2006.01); C08L 89/04 (2006.01); C12N 15/82 (2006.01)
CPC A61L 27/26 (2013.01) [A61K 8/042 (2013.01); A61K 8/65 (2013.01); A61K 8/735 (2013.01); A61L 27/3687 (2013.01); A61Q 19/08 (2013.01); C08L 5/08 (2013.01); C08L 89/04 (2013.01); C12N 15/8257 (2013.01); A61K 2800/59 (2013.01); A61K 2800/81 (2013.01); A61K 2800/91 (2013.01); A61L 2400/06 (2013.01); A61L 2430/34 (2013.01)] 27 Claims
OG exemplary drawing
 
1. A polymerizable solution comprising:
a cross-linkable, plant-derived recombinant type 1 human collagen (rhcollagen);
a hyaluronic acid (HA), a modified HA derivative, a poly(vinyl alcohol) (PVA), a modified PVA derivative, a polyethylene glycol (PEG), a modified PEG derivative, oxidized cellulose (OC), a modified OC derivate, polymethylmethacrylate (PMMA) microspheres, modified PMMA microsphere derivatives, tricalcium phosphate (TCP), a modified TCP derivative, calcium hydroxylapatite (CaHA), a modified CaHA derivative, carboxymethylcellulose, a modified carboxymethylcellulose derivative, crystalline nanocellulose (CNC), a modified CNC derivative, or a combination thereof; and
a photoinitiator.