US 12,186,412 B2
Polymer coatings for brachytherapy devices
Itzhak Kelson, Tel Aviv (IL); Yona Keisari, Ramat Gan (IL); Michael Schmidt, Kfar Saba (IL); and Avia Berkowitz, Modiin (IL)
Assigned to ALPHA TAU MEDICAL LTD., Jerusalem (IL)
Filed by ALPHA TAU MEDICAL LTD., Jerusalem (IL)
Filed on Sep. 20, 2022, as Appl. No. 17/948,280.
Application 17/948,280 is a continuation of application No. 16/610,507, granted, now 11,529,432, previously published as PCT/IB2018/053213, filed on May 9, 2018.
Claims priority of provisional application 62/504,800, filed on May 11, 2017.
Prior Publication US 2023/0014526 A1, Jan. 19, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 51/12 (2006.01); A61K 51/06 (2006.01); A61L 31/10 (2006.01); A61N 5/10 (2006.01)
CPC A61K 51/1282 (2013.01) [A61K 51/06 (2013.01); A61L 31/10 (2013.01); A61N 5/1007 (2013.01); A61L 2420/08 (2013.01); A61N 2005/1025 (2013.01)] 20 Claims
OG exemplary drawing
 
1. An apparatus, comprising:
a support, comprising an outer surface and configured for insertion into a body of a subject;
multiple atoms of an alpha-emitting radionuclide, coupled to the outer surface, wherein the radionuclide radioactively decays to produce a daughter radionuclide; and
a layer of a polymer having a thickness of at least 0.1 micron, wherein the layer of the polymer covers the multiple atoms of the radionuclide to protect the multiple atoms of the radionuclide from being washed away by body fluids, and further wherein the layer of the polymer allows diffusion of the daughter radionuclide through the layer of the polymer.