US 12,186,336 B2
Polysaccharide-polyamine copolymers for removal of phosphate
James W. Mitchell, Durham, NC (US); and Dazhi Yang, Gaithersburg, MD (US)
Assigned to Howard University, Washington, DC (US)
Filed by HOWARD UNIVERSITY, Washington, DC (US)
Filed on Oct. 22, 2020, as Appl. No. 17/077,950.
Application 17/077,950 is a division of application No. 15/560,131, granted, now 10,849,927, previously published as PCT/US2016/023237, filed on Mar. 18, 2016.
Claims priority of provisional application 62/136,220, filed on Mar. 20, 2015.
Prior Publication US 2021/0038638 A1, Feb. 11, 2021
Int. Cl. A61K 31/785 (2006.01); A61K 9/14 (2006.01); A61K 31/738 (2006.01); A61P 7/08 (2006.01); B01J 20/26 (2006.01); B01J 20/28 (2006.01); B01J 20/30 (2006.01); C08B 15/06 (2006.01); C08F 251/02 (2006.01); C08G 73/02 (2006.01); C08G 81/00 (2006.01); C08G 83/00 (2006.01); C08J 9/16 (2006.01); C08L 1/08 (2006.01); C08L 3/20 (2006.01); C08L 5/02 (2006.01); C08L 5/08 (2006.01); C08G 101/00 (2006.01)
CPC A61K 31/785 (2013.01) [A61K 9/14 (2013.01); A61K 31/738 (2013.01); A61P 7/08 (2018.01); B01J 20/264 (2013.01); B01J 20/267 (2013.01); B01J 20/28004 (2013.01); B01J 20/28078 (2013.01); B01J 20/28085 (2013.01); B01J 20/3085 (2013.01); C08B 15/06 (2013.01); C08F 251/02 (2013.01); C08G 73/0206 (2013.01); C08G 81/00 (2013.01); C08G 83/002 (2013.01); C08J 9/16 (2013.01); C08L 1/08 (2013.01); C08L 3/20 (2013.01); C08L 5/02 (2013.01); C08L 5/08 (2013.01); C08G 2101/00 (2013.01); C08G 2210/00 (2013.01); C08J 2205/022 (2013.01); C08J 2207/10 (2013.01); C08J 2387/00 (2013.01)] 6 Claims
OG exemplary drawing
 
1. A method to effect removal of phosphate from an aqueous phosphate solution, the method comprising applying a protonated particulate polysaccharide- polyamine copolymeric material having a three-dimensional structure, the particulate polysaccharide-polyamine polymeric material comprising:
selectively oxidized polysaccharides having a 2,3 di-aldehyde moiety; and
amino polymers which provide a cationic amino functionality, the amino polymers covalently cross linking the selectively oxidized polysaccharides to provide a particulate polysaccharide-polyamine copolymer and copolymeric material having an amino functionality which when protonate will provide the cationic copolymeric material with a nitrogen content of at least 12.3 wt. %, the cationic particulate polysaccharide-polyamine copolymer and cationic copolymeric material being water insoluble,
wherein the selectively oxidized polysaccharides have β-1,6-glycosidic bonds.