US 12,186,300 B2
Esters for treatment of ocular inflammatory conditions
Annabelle Gallois-Bernos, Jacksonville, FL (US); Frank F. Molock, Jr., Birmingham (GB); Carrie L. Davis, St. Augustine, FL (US); Kathrine Osborn Lorenz, Jacksonville, FL (US); James K. Young, Ponte Vedra Beach, FL (US); Kristy L. Canavan, Jacksonville, FL (US); and Fang Lu, St. Augustine, FL (US)
Assigned to Johnson & Johnson Vision Care, Inc., Jacksonville, FL (US)
Filed by Johnson & Johnson Vision Care, Inc., Jacksonville, FL (US)
Filed on Aug. 20, 2021, as Appl. No. 17/445,520.
Application 17/445,520 is a continuation of application No. 16/460,208, filed on Jul. 2, 2019, granted, now 11,096,919.
Application 16/460,208 is a continuation of application No. 13/495,049, filed on Jun. 13, 2012, granted, now 10,383,839, issued on Aug. 20, 2019.
Claims priority of provisional application 61/503,158, filed on Jun. 30, 2011.
Prior Publication US 2021/0379005 A1, Dec. 9, 2021
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/232 (2006.01); A61K 9/00 (2006.01); A61K 31/16 (2006.01); A61K 31/201 (2006.01); A61K 31/202 (2006.01); A61K 31/203 (2006.01); A61K 31/215 (2006.01); A61K 31/557 (2006.01); A61K 31/5575 (2006.01); A61K 31/661 (2006.01); A61K 31/683 (2006.01); A61K 9/08 (2006.01)
CPC A61K 31/232 (2013.01) [A61K 9/0048 (2013.01); A61K 31/16 (2013.01); A61K 31/201 (2013.01); A61K 31/202 (2013.01); A61K 31/203 (2013.01); A61K 31/215 (2013.01); A61K 31/557 (2013.01); A61K 31/5575 (2013.01); A61K 31/661 (2013.01); A61K 31/683 (2013.01); A61K 9/08 (2013.01)] 14 Claims
 
1. An ocular product comprising:
(a) a contact lens; and
(b) a packaging formulation comprising:
an ester of an anti-inflammatory lipid mediator that is selected from the group consisting of eicosapentaenoic acid ethyl ester and alpha-linolenic acid ethyl ester and mixtures thereof; and
an aqueous delivery system;
wherein the majority of the anti-inflammatory lipid mediator is present in an ester form, and wherein the ester is dispersed in the packaging formulation;
wherein the contact lens is immersed in the packaging formulation.