	US 12,186,297 B2
	Compositions and methods for increasing lean-to-fat mass ratio
Gary Millet, Salt Lake City, UT (US)
Assigned to AXCESS GLOBAL SCIENCES, LLC, Salt Lake City, UT (US)
Filed by AXCESS GLOBAL SCIENCES, LLC, Salt Lake City, UT (US)
Filed on Aug. 5, 2021, as Appl. No. 17/394,649.
Claims priority of provisional application 63/070,532, filed on Aug. 26, 2020.
Prior Publication US 2022/0062216 A1, Mar. 3, 2022
Int. Cl. A61K 31/22 (2006.01); A61K 31/12 (2006.01); A61K 31/19 (2006.01)

CPC A61K 31/22 (2013.01) [A61K 31/12 (2013.01); A61K 31/19 (2013.01)]

20 Claims

1. A composition comprising:

an exogenous ketone body component selected from the group consisting of beta-hydroxybutyrate (BHB) salts, BHB esters, beta-hydroxybutyric acid, and combinations thereof; and

exogenous hydroxymethyl butyrate (HMB),

wherein the composition includes a ratio of exogenous ketone body component to exogenous HMB from about 4.5:1 to about 2.5:1 so as to be effective to increase lean mass to fat mass ratio in a mammal.