	US 12,186,283 B2
	Bismuth-thiol compositions and methods of use
Brett Hugh James Baker, Bozeman, MT (US); and Jeffrey W. Millard, Bozeman, MT (US)
Assigned to MICROBION CORPORATION, Bozeman, MT (US)
Filed by Microbion Corporation, Bozeman, MT (US)
Filed on Oct. 3, 2022, as Appl. No. 17/959,032.
Application 17/959,032 is a division of application No. 16/528,145, filed on Jul. 31, 2019, granted, now 11,464,749.
Claims priority of provisional application 62/800,925, filed on Feb. 4, 2019.
Claims priority of provisional application 62/712,563, filed on Jul. 31, 2018.
Prior Publication US 2023/0165808 A1, Jun. 1, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/095 (2006.01); A61K 9/00 (2006.01); A61P 31/04 (2006.01)

CPC A61K 31/095 (2013.01) [A61K 9/0073 (2013.01); A61P 31/04 (2018.01)]

18 Claims

1. An aerosol comprising a plurality of dispersed liquid droplets in a gas, said liquid droplets comprising a bismuth-thiol (BT) composition comprising bismuth-1,2-ethanedithiol (BisEDT) suspended therein, wherein the BT composition comprises a plurality of BisEDT particles having a D90 of less than about 2 μm as measured by laser diffraction; and

wherein at least 70% of the total number of dispersed liquid droplets have a mass median aerodynamic diameter (MMAD) from about 0.4 μm to about 5 μm as measured by cascade impaction or laser time of flight.