US 12,186,124 B2
System and method for timing calibration of a detection system of a TOF-PET scanner
Pawel Moskal, Czulowek (PL); and Kamil Dulski, Raciborz (PL)
Assigned to UNIWERSYTET JAGIELLONSKI, Cracow (PL)
Appl. No. 18/014,195
Filed by UNIWERSYTET JAGIELLONSKI, Cracow (PL)
PCT Filed Jul. 9, 2021, PCT No. PCT/EP2021/069190
§ 371(c)(1), (2) Date Jan. 3, 2023,
PCT Pub. No. WO2022/013105, PCT Pub. Date Jan. 20, 2022.
Claims priority of application No. 434697 (PL), filed on Jul. 16, 2020.
Prior Publication US 2023/0255585 A1, Aug. 17, 2023
Int. Cl. A61B 6/58 (2024.01); G01T 1/29 (2006.01); G01T 7/00 (2006.01)
CPC A61B 6/585 (2013.01) [G01T 1/2985 (2013.01); G01T 7/005 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A method for a TOF-PET scanner, the TOF-PET scanner comprising a scintillation chamber and a detection system, the detection system comprising detection modules (X) that surround the scintillation chamber; the method comprising:
providing a radiation source in the scintillation chamber, wherein the radiation source is configured to emit, in the scintillation chamber, both positrons for annihilation with emission of annihilation quanta and de-excitation quanta having an energy different from an energy of the annihilation quanta;
registering the annihilation quanta deposited in the detection modules (X) as registered annihilation quanta and the de-excitation quanta deposited in the detection modules (X) as registered de-excitation quanta;
selecting the registered annihilation quanta and the registered de-excitation quanta based on times of registration and energies of the deposited quanta;
assigning the annihilation quanta and the de-excitation quanta to common events;
wherein the method further comprises, for each detection module (X) being calibrated:
determining distributions of lifetimes of positrons based on differences of the times of registration of annihilation quanta and of the times of registration of the de-excitation quanta assigned to the common events and registered by the module being calibrated;
extracting, from the determined distributions of lifetimes of positions, a distribution of lifetimes of positrons with annihilation by para-positronium; and
determining a time delay constant based on the extracted distributions of lifetimes of positrons with annihilation by a para-positronium.