US 12,186,051 B2
Systems and methods for determining and communicating levels of bilirubin and other subcutaneous substances
Matthew James Clemente, San Jose, CA (US); George Stavis, Dobbs Ferry, NY (US); Robert Stavis, Bryn Mawr, PA (US); Mary Elizabeth Lemma, West Chester, PA (US); and Steven P. Getz, Malvern, PA (US)
Assigned to Bilibaby, LLC, Phoenixville, PA (US)
Filed by Bilibaby, LLC, Phoenixville, PA (US)
Filed on Aug. 26, 2022, as Appl. No. 17/897,108.
Claims priority of provisional application 63/238,058, filed on Aug. 27, 2021.
Prior Publication US 2023/0069111 A1, Mar. 2, 2023
Int. Cl. A61B 5/00 (2006.01); A61B 5/1455 (2006.01); G16H 40/67 (2018.01)
CPC A61B 5/0022 (2013.01) [A61B 5/1455 (2013.01); G16H 40/67 (2018.01)] 17 Claims
OG exemplary drawing
 
1. A system for determining levels or concentrations of a substance in a patient's skin based on an optical property of the substance, comprising:
a computing device comprising a memory and a processor;
a software application stored in the memory of the computing device and configured to run on the processor of the computing device; and
a module in communication with the computing device and separated and detached from the computing device, said module comprising:
a data communication capability, wherein the data includes light intensity or wavelength information;
a status indicator that provides visual, audible, or tactile confirmation that the module is ready for operation;
two or more light sources that provide light which penetrates the patient's skin to a subcutaneous level, wherein the two or more light sources are configured to provide different wavelengths of light sequentially at multiple points in time in rapid succession;
multiple optical pathways that transmit the light from the two or more light sources that is reflected and scattered from the patient's skin from the subcutaneous level to one or more light sensors that detect the light from the two or more light sources that is reflected and scattered from the patient's skin from the subcutaneous level sequentially at multiple points in time in rapid succession;
an ambient light sensor; and
a power source;
wherein the software application is configured to determine the levels or concentrations of the substance in the patient's skin based on a measurement of light intensity or wavelength from the light sensor, and
wherein the software application is configured to account for light intensity of ambient light measured from the ambient light sensor in calculating a net light intensity of light reflected and scattered from the patient's skin.