US 11,854,281 B2
System, method, and computer-accessible medium for processing brain images and extracting neuronal structures
Arie Kaufman, Plainview, NY (US); and Saeed Boorboor, Lake Grove, NY (US)
Assigned to The Research Foundation for the State University of New York, Albany, NY (US)
Filed by THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, Albany, NY (US)
Filed on Aug. 17, 2020, as Appl. No. 16/994,885.
Claims priority of provisional application 62/887,719, filed on Aug. 16, 2019.
Prior Publication US 2021/0049338 A1, Feb. 18, 2021
Int. Cl. G06V 20/69 (2022.01); G06T 7/00 (2017.01)
CPC G06V 20/695 (2022.01) [G06T 7/0012 (2013.01); G06T 2207/10056 (2013.01); G06T 2207/20021 (2013.01); G06T 2207/30016 (2013.01); G06T 2207/30024 (2013.01)] 22 Claims
OG exemplary drawing
 
1. A non-transitory computer-accessible medium having stored thereon computer-executable instructions for generating at least one image of at least one anatomical structure in at least one biological sample, wherein, when a computing arrangement executes the instructions, the computing arrangement is configured to perform procedures comprising:
receiving first wide field microscopy imaging information for the biological sample; generating second imaging information by applying a gradient-based distance transform to the first imaging information, wherein the gradient-based distance transform comprises:
determining a global minimum intensity value based on voxels in the first imaging information;
determining at least one seed voxel based on the global minimum intensity value;
determining an intensity value for neighboring voxels of the at least one seed voxel;
determining a particular neighbor voxel of the neighboring voxels that has a highest intensity; and
adding the intensity value for the at least one seed voxel to the particular neighbor voxel; and
generating the at least one image based on the second imaging information.