US 11,854,191 B2
Image processing method for displaying cells of a plurality of overall images
Christian Marzahl, Erlangen (DE); Stefan Gerlach, Groß Groenau (DE); Joern Voigt, Luebeck (DE); and Christine Kroeger, Ahrensboek (DE)
Assigned to EUROIMMUN Medizinische Labordiagnostika AG, Luebeck (DE)
Filed by EUROIMMUN Medizinische Labordiagnostika AG, Luebeck (DE)
Filed on Mar. 2, 2021, as Appl. No. 17/189,449.
Claims priority of application No. 20160329 (EP), filed on Mar. 2, 2020.
Prior Publication US 2021/0272279 A1, Sep. 2, 2021
Int. Cl. G06T 7/00 (2017.01); G16H 30/40 (2018.01); G06F 18/2431 (2023.01)
CPC G06T 7/0012 (2013.01) [G06F 18/2431 (2023.01); G16H 30/40 (2018.01); G06T 2207/10056 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30204 (2013.01)] 9 Claims
OG exemplary drawing
 
1. An image processing system for displaying cells of a plurality of overall images, each respective overall image representing a respective patient tissue sample or a respective patient cell sample, the system comprising a server and furthermore a client in communication with the server via a data network:
the server configured to:
provide the overall images;
detect individual cell images in the overall images by means of a computer-assisted algorithm;
determine classification data by means of the computer-assisted algorithm,
wherein the classification data indicate a respective unique mapping of a respective detected cell image to one of a plurality of cell classes, and
wherein the classification data further have a respective measure of confidence in respect of the respective unique mapping; and
generate respective class images for the respective cell classes,
wherein a class image of a cell class reproduces the cell images mapped to the cell class in a regular arrangement and with a predetermined order, and
wherein the order of the mapped cell images is chosen on the basis of the measures of confidence of the mapped cell images; and
the server is further configured to:
generate an annotation data record that indicates, for each class image:
respective mappings of the respective cell images to a cell class corresponding to the class image; and
respective local positions of the respective cell images within the class images; and
receive, from the client, a request for a portion of a class image; and
transmit, to the client, the portion and at least one partial annotation data record corresponding to the portion; and
the client is further configured to:
temporarily store the at least one partial annotation data record;
generate respective optical markings for respective cell images of the portion on the basis of at least the partial annotation data record,
wherein the respective optical markings indicate respective mappings of the respective cell images to a cell class corresponding to the class image; and
display the portion and the associated optical markings on a display unit,
wherein the portion comprises a plurality of cell images of overall images in respect of the mapping of the cell images to a certain cell class.