US 11,853,013 B2
Systems and methods for indicating the time elapsed since the occurrence of a triggering event
Frank Gu, Toronto (CA); and Paul Chen, Toronto (CA)
Assigned to Johnson & Johnson Vision Care, Inc., Jacksonville, FL (US)
Filed by Johnson & Johnson Vision Care, Inc., Jacksonville, FL (US)
Filed on Jun. 15, 2020, as Appl. No. 16/901,113.
Prior Publication US 2021/0389731 A1, Dec. 16, 2021
Int. Cl. G04F 13/02 (2006.01); G01N 31/22 (2006.01); G01N 21/78 (2006.01); B82Y 20/00 (2011.01); A61K 33/38 (2006.01); A61L 15/56 (2006.01); A61L 15/44 (2006.01); G01N 21/77 (2006.01)
CPC G04F 13/02 (2013.01) [G01N 31/229 (2013.01); A61K 33/38 (2013.01); A61L 15/44 (2013.01); A61L 15/56 (2013.01); B82Y 20/00 (2013.01); G01N 21/77 (2013.01); G01N 21/78 (2013.01)] 46 Claims
OG exemplary drawing
 
1. A system for visually indicating the time elapsed since an article has been removed from a package, the system comprising:
an indicator disposed on or within the article, wherein the article is enclosed within a sealable receptacle of the package; and
a trigger disposed within the receptacle and in contact with the indicator;
wherein the indicator is responsive to a change in a concentration of the trigger in contact with the indicator,
wherein the indicator comprises a population of nanoparticles stabilized by a capping agent, and wherein the trigger comprises a solution comprising the capping agent in contact with the indicator,
wherein when the article is removed from the receptacle and placed in contact with a solution containing a lower concentration of the trigger, the capping agent disassociates from the nanoparticles, thereby inducing aggregation of the population of nanoparticles; and
wherein aggregation of the population of nanoparticles results in a color change.