US 11,852,640 B2
Hematology analyzers and methods of operation
Carlos Ramirez, Miami, FL (US); Nery Ortiz, Miami, FL (US); and Milton Swaby, Pembroke Pines, FL (US)
Assigned to Beckman Coulter, Inc., Brea, CA (US)
Filed by Beckman Coulter, Inc., Brea, CA (US)
Filed on Oct. 25, 2018, as Appl. No. 16/170,389.
Claims priority of provisional application 62/578,239, filed on Oct. 27, 2017.
Prior Publication US 2019/0128906 A1, May 2, 2019
Int. Cl. G01N 35/00 (2006.01); G01N 15/10 (2006.01); G01N 15/14 (2006.01); G01N 15/02 (2006.01); G01N 33/49 (2006.01); G01N 15/00 (2006.01); G16H 40/40 (2018.01); G16H 10/40 (2018.01); G16H 40/60 (2018.01); G16H 50/20 (2018.01)
CPC G01N 35/00623 (2013.01) [G01N 15/0205 (2013.01); G01N 15/1012 (2013.01); G01N 15/1031 (2013.01); G01N 15/1459 (2013.01); G01N 33/4915 (2013.01); G01N 35/00693 (2013.01); G16H 10/40 (2018.01); G16H 40/40 (2018.01); G16H 40/60 (2018.01); G16H 50/20 (2018.01); G01N 2015/008 (2013.01); G01N 2015/0069 (2013.01); G01N 2015/0073 (2013.01); G01N 2015/0084 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1087 (2013.01); G01N 2015/1402 (2013.01); G01N 2015/1493 (2013.01)] 23 Claims
OG exemplary drawing
 
1. An automated system for evaluating an infection status associated with a blood sample obtained from an individual, the automated system comprising:
a transducer operable to measure a control material as the control material passes through an aperture, the control material comprising a first cell population and a second cell population, wherein the first cell population is different from the second cell population;
a processor; and
a non-transitory computer readable medium storing a plurality of instructions that when executed by the processor, cause the automated system to:
obtain current data for the control material,
calculate a first value, wherein the first value is a distribution width value of the first cell population,
calculate a second value, wherein the second value is a distribution width value of the second cell population,
perform a first comparison for a hematology parameter by comparing the first value to a first reference range for the hematology parameter,
perform a second comparison for the hematology parameter by comparing the second value to a second reference range for the hematology parameter, and
classify an operational status of the automated system based on the first comparison and the second comparison.