CPC C07D 487/04 (2013.01) [A61P 35/00 (2018.01); C07B 2200/13 (2013.01)] | 20 Claims |
1. A method for treating cancer in warm-blooded animal in need of such treatment, which comprises administering to the warm-blooded animal a therapeutically effective amount of a compound of Formula (I):
or a pharmaceutically acceptable salt thereof, wherein:
R1 and R2 each independently represent hydrogen or methyl;
X represents CH2 or O;
Ring A and Ring B each independently represent a ring selected from phenyl, pyridinyl, pyrazinyl, pyrimidinyl and pyridazinyl, wherein each of Ring A and Ring B are independently optionally substituted with one or more substituents selected from C1-3 alkyl and C1-3 alkoxy;
Ring C represents a 5 to 9 membered monocyclic or bicyclic saturated heterocycloalkyl optionally containing one or more additional heteroatoms independently selected from O, N and S, wherein Ring C is optionally substituted with one or more substituents selected from C1-3 alkyl, optionally substituted with methoxy or hydroxyl; dioxo, C0-2 alkyl-C(O)N(Me)2, C(O)C1-2 alkyl and S(O)2C1-2 alkyl.
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