US 11,850,314 B2
Illumination of light diffusing optical fibers, illumination of blue-violet light delivery systems, blue-violet light delivery systems, and methods for blue-violet light induced disinfection
William Spencer Klubben, III, Boston, MA (US); and Kaitlyn Matias Rees, Medford, MA (US)
Assigned to Corning Incorporated, Corning, NY (US)
Appl. No. 16/962,674
Filed by CORNING INCORPORATED, Corning, NY (US)
PCT Filed Jan. 16, 2019, PCT No. PCT/US2019/013733
§ 371(c)(1), (2) Date Jul. 16, 2020,
PCT Pub. No. WO2019/143647, PCT Pub. Date Jul. 25, 2019.
Claims priority of provisional application 62/622,503, filed on Jan. 26, 2018.
Claims priority of provisional application 62/617,784, filed on Jan. 16, 2018.
Prior Publication US 2020/0360548 A1, Nov. 19, 2020
Int. Cl. A61L 2/08 (2006.01); A61L 2/26 (2006.01); G02B 6/02 (2006.01)
CPC A61L 2/084 (2013.01) [A61L 2/26 (2013.01); G02B 6/02395 (2013.01); A61L 2202/11 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A light delivery system configured to irradiate a pathogen sample comprising an amount of colony forming units with a blue-violet light for an exposure time from about 30 minutes to about 48 hours such that the amount of colony forming units of the pathogen sample are reduced by about a 4-Log reduction to about a 9-Log reduction, the light delivery system comprising:
a blue-violet light irradiating device that emits the blue-violet light comprising an average power density of about 5 mW/cm2 to about 30 mW/cm2 at a wavelength from about 380 nm to about 495 nm; and
a light source optically connected to the blue-violet light irradiating device,
wherein the blue-violet light irradiating device comprises one or more light diffusing optical fibers comprising:
a core;
a cladding surrounding the core;
an outer surface;
a plurality of scattering structures positioned within the core, the cladding, or both the core and the cladding, wherein the plurality of scattering structures scatter the blue-violet light propagating along the one or more light diffusing optical fibers toward the outer surface and a portion of the blue-violet light diffuses through the outer surface; and
a primary coating layer surrounding the cladding,
wherein the primary coating layer comprises a cycloaliphatic epoxy and is doped with a plurality of scattering particles comprising a greater refractive index than a refractive index of the cycloaliphatic epoxy;
wherein the core comprises glass doped with 300 ppm or more of a hydroxyl material and the cladding comprises glass doped with 300 ppm or more of a hydroxyl material.