CPC A61L 2/084 (2013.01) [A61L 2/26 (2013.01); G02B 6/02395 (2013.01); A61L 2202/11 (2013.01)] | 7 Claims |
1. A light delivery system configured to irradiate a pathogen sample comprising an amount of colony forming units with a blue-violet light for an exposure time from about 30 minutes to about 48 hours such that the amount of colony forming units of the pathogen sample are reduced by about a 4-Log reduction to about a 9-Log reduction, the light delivery system comprising:
a blue-violet light irradiating device that emits the blue-violet light comprising an average power density of about 5 mW/cm2 to about 30 mW/cm2 at a wavelength from about 380 nm to about 495 nm; and
a light source optically connected to the blue-violet light irradiating device,
wherein the blue-violet light irradiating device comprises one or more light diffusing optical fibers comprising:
a core;
a cladding surrounding the core;
an outer surface;
a plurality of scattering structures positioned within the core, the cladding, or both the core and the cladding, wherein the plurality of scattering structures scatter the blue-violet light propagating along the one or more light diffusing optical fibers toward the outer surface and a portion of the blue-violet light diffuses through the outer surface; and
a primary coating layer surrounding the cladding,
wherein the primary coating layer comprises a cycloaliphatic epoxy and is doped with a plurality of scattering particles comprising a greater refractive index than a refractive index of the cycloaliphatic epoxy;
wherein the core comprises glass doped with 300 ppm or more of a hydroxyl material and the cladding comprises glass doped with 300 ppm or more of a hydroxyl material.
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