CPC A61K 31/46 (2013.01) [A61K 9/0034 (2013.01); A61M 31/002 (2013.01)] | 27 Claims |
1. A method of reducing bladder spasms and involuntary detrusor contractions in a patient without suppressing overall bladder function, comprising:
locally administering trospium into the bladder of the patient continuously over a treatment period from 30 days to 180 days to achieve a sustained concentration of trospium in urine in the bladder sufficient to produce a therapeutic concentration of trospium in bladder tissue,
wherein the locally administering into the patient's bladder is continuous at a mean average amount of from 0.15 mg/day to 15 mg/day of the trospium for the treatment period.
|