US 11,850,212 B2
Microlayer coextrusion to create a time-release drug substance delivery product
Richard Guillemette, West Warwick, RI (US); Robert Peters, West Warwick, RI (US); and Christopher Hummel, Providence, RI (US)
Assigned to Guill Tool & Engineering Co., Inc., West Warwick, RI (US)
Filed by Guill Tool & Engineering Co., Inc., West Warwick, RI (US)
Filed on Jun. 23, 2020, as Appl. No. 16/909,496.
Application 16/909,496 is a continuation of application No. 16/245,581, filed on Jan. 11, 2019, granted, now 10,695,267.
Application 16/245,581 is a continuation of application No. 13/748,542, filed on Jan. 23, 2013, granted, now 10,195,114, issued on Feb. 5, 2019.
Application 13/748,542 is a continuation in part of application No. 13/681,413, filed on Nov. 19, 2012, abandoned.
Application 13/681,413 is a continuation in part of application No. 13/336,825, filed on Dec. 23, 2011, granted, now 9,381,712, issued on Jul. 5, 2016.
Claims priority of provisional application 61/561,165, filed on Nov. 17, 2011.
Claims priority of provisional application 61/460,042, filed on Dec. 23, 2010.
Prior Publication US 2020/0315920 A1, Oct. 8, 2020
This patent is subject to a terminal disclaimer.
Int. Cl. A61J 3/00 (2006.01); A61J 3/06 (2006.01); A61J 3/07 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); A61L 29/14 (2006.01); A61L 29/16 (2006.01); A61L 31/16 (2006.01); A61L 31/14 (2006.01)
CPC A61J 3/00 (2013.01) [A61J 3/06 (2013.01); A61J 3/07 (2013.01); A61K 9/0092 (2013.01); A61K 9/2072 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); A61L 29/14 (2013.01); A61L 29/16 (2013.01); A61L 31/14 (2013.01); A61L 31/16 (2013.01); A61L 2400/12 (2013.01); A61L 2400/18 (2013.01)] 6 Claims
OG exemplary drawing
 
1. An extrusion process for preparing a medical device comprising the steps of:
combining at least two flow streams of laminated polymer, wherein the laminated polymer flow streams contain laminations which have micro or nanometer thickness;
joining the at least two flow streams of laminated polymer within a die to form a continuous cumulated laminated flow within the die, extruding the continuous cumulated laminated flow to produce an extruded multilayered polymer solid of two or more annular rings, a cross-section of the extruded multilayered polymer solid having two or more annular rings with a micro or nanometer radial thickness, wherein said extruded multilayered polymer solid is further processed into a medical device which is an implantable device.