CPC C07K 14/4703 (2013.01) [A61K 38/03 (2013.01); C07K 4/00 (2013.01); C07K 7/08 (2013.01); A61K 38/00 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01)] | 21 Claims |
1. A peptide comprising:
[X1]p1[X2]p2—X3X4X5X6X7X8X9X10—[X11]p11[X12]p12[X13]p13,
wherein:
each of p1, p2, p11, p12 and p13 is independently 0 or 1;
each of X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12, and X13 is independently an amino acid residue;
at least two of X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12, and X13 comprise side chains that are linked together to form a staple, wherein the peptide comprises a structure selected from:
wherein each X is independently an amino acid residue.
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