CPC C07D 235/30 (2013.01) [C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 405/12 (2013.01); C07D 413/04 (2013.01)] | 20 Claims |
1. A compound represented by a formula:
wherein:
D is optionally substituted cyclobutyl, optionally substituted phenyl, optionally substituted isoxazolyl, optionally substituted pyridinyl, isopropyl, or t-butyl;
A is C1-8 alkyl;
X is optionally substituted phenyl;
Y is OH;
R1 is H, Cl, Br, CN, OCH3, CF3, —CO2CH2CH3, C1-4 alkyl, or C1-4 hydroxyalkyl; and
R2 is H, F, —CH2OH, —CO2Me, or —C(CH3)2OH;
R3 is H, F, Cl, Br, I, or a substituent having a molecular weight of 15 Da to 200 Da and consisting of 2 to 5 chemical elements, wherein the chemical elements are independently C, H, O, N, S, F, Cl, or Br; and
R4 is H, —CH3, or —CF3;
or a pharmaceutically acceptable salt thereof.
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