CPC A61L 27/24 (2013.01) [A61K 8/042 (2013.01); A61K 8/735 (2013.01); A61L 27/26 (2013.01); A61L 27/3695 (2013.01); A61L 27/52 (2013.01); A61Q 19/08 (2013.01); A61K 2800/91 (2013.01); A61L 2400/06 (2013.01); A61L 2430/34 (2013.01)] | 11 Claims |
1. A hydrogel composition comprising:
(i) about 16 mg/ml to about 24 mg/ml of a hyaluronic acid, and
(ii) about 3 mg/ml to about 6 mg/ml of a collagen,
wherein the weight ratio of the hyaluronic acid to the collagen is from 3:1 to 7:1;
wherein the hyaluronic acid is crosslinked with the collagen via a plurality of crosslink units, wherein the hyaluronic acid is crosslinked with the collagen via a water-soluble carbodiimide, wherein at least a portion of the crosslink units comprise an amide bond, and wherein the composition has a storage modulus value of between about 850 Pa and about 5,000 Pa.
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