CPC A61K 39/0011 (2013.01) [A61K 9/127 (2013.01); A61K 31/7088 (2013.01); A61K 31/712 (2013.01); A61K 31/713 (2013.01); A61K 39/00111 (2018.08); A61K 39/001106 (2018.08); A61K 39/001132 (2018.08); A61K 39/001151 (2018.08); A61K 39/001156 (2018.08); A61K 39/001157 (2018.08); A61K 39/001162 (2018.08); A61K 39/001164 (2018.08); A61K 39/001166 (2018.08); A61K 39/001176 (2018.08); A61K 39/001181 (2018.08); A61K 39/001182 (2018.08); A61K 39/001184 (2018.08); A61K 39/001186 (2018.08); A61K 39/001188 (2018.08); A61K 39/001189 (2018.08); A61K 39/001191 (2018.08); A61K 39/001192 (2018.08); A61K 39/001193 (2018.08); A61K 39/001194 (2018.08); A61K 39/001195 (2018.08); A61K 39/001197 (2018.08); A61K 45/06 (2013.01); A61K 47/554 (2017.08); A61K 47/6917 (2017.08); C12N 15/111 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3515 (2013.01); C12N 2320/32 (2013.01)] | 9 Claims |
1. A composition comprising an sHDL nanoparticle,
wherein the sHDL nanoparticle comprises (i) a phospholipid selected from 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) and dipalmitoylphosphatidylcholine (DPPC), (ii) a thiol-reactive phospholipid, and (iii) an apolipoprotein mimetic having the sequence PVLDLFRELLNELLEALKQKLK (SEQ ID NO: 4).
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