US 11,833,158 B2
Compositions comprising omega-3 fatty acids, 17-HDHA and 18-HEPE and methods of using same
Charles Nicholas Serhan, Needham, MA (US); Fernando Moreno Egea, Alcobendas (ES); and Joan Clària Enrich, Sant Esteve Sesrovires (ES)
Assigned to SOLUTEX NA LLC, Miami, FL (US)
Filed by Solutex NA LLC, Miami, FL (US)
Filed on May 14, 2021, as Appl. No. 17/320,977.
Application 17/320,977 is a continuation of application No. 17/070,401, filed on Oct. 14, 2020, granted, now 11,020,406.
Application 17/070,401 is a continuation of application No. 16/843,416, filed on Apr. 8, 2020, granted, now 11,559,529.
Application 16/843,416 is a continuation of application No. 15/757,023, granted, now 10,653,703, issued on May 19, 2020, previously published as PCT/US2016/050397, filed on Sep. 6, 2016.
Claims priority of provisional application 62/213,958, filed on Sep. 3, 2015.
Prior Publication US 2022/0008434 A1, Jan. 13, 2022
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 31/202 (2006.01); A23L 33/12 (2016.01); A61P 29/00 (2006.01); A61K 31/557 (2006.01); A61K 45/06 (2006.01); C11B 3/00 (2006.01); C11B 1/10 (2006.01); A23D 9/00 (2006.01); C11C 3/10 (2006.01)
CPC A61K 31/557 (2013.01) [A23D 9/00 (2013.01); A23L 33/12 (2016.08); A61K 31/202 (2013.01); A61K 45/06 (2013.01); A61P 29/00 (2018.01); C11B 1/104 (2013.01); C11B 3/001 (2013.01); C11C 3/10 (2013.01)] 18 Claims
 
1. A composition, comprising:
docosahexaenoic acid (“DHA”) in an amount of about 20% to about 95%, by weight, of the composition; and
17-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid (“17-HDHA”), 14-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid (“14-HDHA”), 15-hydroxy-5Z,8Z,11Z,13E,17Z-eicosapentaenoic acid (“15-HEPE”), and 18-hydroxy-5Z,8Z,11Z,14Z,16E-eicosapentaenoic acid (“18-HEPE”), wherein the 18-HEPE is present in an amount of 0.02% to about 1%, by weight, of the composition and the 17-HDHA is present in an amount of 0.01% to about 1%, by weight, of the composition.