CPC A01K 67/0337 (2013.01) [A01K 67/0339 (2013.01); C07K 14/195 (2013.01); C12N 1/205 (2021.05); C12N 9/22 (2013.01); C12N 9/6472 (2013.01); C12N 15/87 (2013.01); A01K 2217/052 (2013.01); A01K 2217/206 (2013.01); A01K 2227/706 (2013.01); A01K 2267/02 (2013.01); C07K 2319/21 (2013.01); C12R 2001/01 (2021.05)] | 4 Claims |
1. A genetically modified arthropod, said arthropod comprising:
(i) a bacterial operon or two independent chromosomal insertions encoding at least two cytoplasmic incompatibility factors, wherein the bacterial operon or the two independent chromosomal insertions is from Wolbachia;
wherein the bacterial operon or the two independent chromosomal insertions encode: the cytoplasmic incompatibility factors WD0631 and WD0632; and
wherein WD0631 is encoded by SEQ ID NO: 25; and
(ii) a promoter operably linked to the bacterial operon or the two independent chromosomal insertions;
wherein the expression of the cytoplasmic incompatibility factors in a male arthropod causes a reduction in viable offspring in comparison to a male arthropod lacking the cytoplasmic incompatibility factors.
|