CPC A61K 31/155 (2013.01) [A61P 31/04 (2018.01); A61K 45/06 (2013.01)] | 10 Claims |
1. A method for treating a patient with an infection from Pseudomonas aeruginosa via virulence factor inhibition, comprising steps of:
administering to the patient a therapeutically effective dose of guanfacine, an analog or derivative of guanfacine, or a pharmaceutically acceptable salt thereof,
wherein the analog or derivative of guanfacine has the structure R1—R2—CONH—R3, where R1 is an optionally substituted phenyl or benzyl group, R2 is a methylene unit or a C1-C6 alkyl group that is saturated or unsaturated, and R3 is a carboxamidine.
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