| US 11,813,059 B2 | ||
| Sensor for a continuous biological monitor having nitric oxide releasing compound | ||
| Qinyi Yan, San Diego, CA (US); Robert James Boock, Carlsbad, CA (US); Jessie Haskamp, San Diego, CA (US); and Huashi Zhang, San Juan Capistrano, CA (US) | ||
| Assigned to Zense-Life Inc., Carlsbad, CA (US) | ||
| Filed by Zense-Life Inc., Carlsbad, CA (US) | ||
| Filed on Nov. 30, 2021, as Appl. No. 17/457,004. | ||
| Prior Publication US 2023/0165493 A1, Jun. 1, 2023 | ||
| Int. Cl. A61B 5/145 (2006.01); A61B 5/1486 (2006.01); A61B 5/266 (2021.01); A61B 5/265 (2021.01); A61B 5/268 (2021.01) | ||
| CPC A61B 5/14865 (2013.01) [A61B 5/14532 (2013.01); A61B 5/265 (2021.01); A61B 5/266 (2021.01); A61B 5/268 (2021.01); A61B 2562/125 (2013.01)] | 20 Claims |
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1. A subcutaneous sensor for use with a continuous glucose monitor comprising:
i) a reference electrode comprising:
a reference substrate;
an ion limiting layer over the reference substrate;
ii) a working electrode comprising:
a conductive substrate;
an interference layer over the conductive substrate;
an enzyme layer over the interference layer, the enzyme layer comprising an enzyme for reacting with in-vivo glucose in body fluid of a patient;
a glucose limiting layer over the enzyme layer that limits an amount of the in-vivo glucose from the body fluid of the patient that passes to the enzyme layer; and
iii) a composition for releasing nitric oxide (NO) comprising:
a NO release compound;
a hydrophilic material;
a hydrophobic material;
wherein the composition is on the reference electrode.
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