US 11,810,685 B2
Early detection of radioisotope generator end life
Adrian Nunn, Lambertville, NJ (US)
Assigned to Bracco Diagnostics Inc., Monroe Township, NJ (US)
Appl. No. 17/042,355
Filed by BRACCO DIAGNOSTICS INC., Monroe Township, NJ (US)
PCT Filed Mar. 28, 2019, PCT No. PCT/US2019/024515
§ 371(c)(1), (2) Date Sep. 28, 2020,
PCT Pub. No. WO2019/191386, PCT Pub. Date Oct. 3, 2019.
Claims priority of provisional application 62/649,556, filed on Mar. 28, 2018.
Prior Publication US 2021/0020322 A1, Jan. 21, 2021
Int. Cl. G21G 1/00 (2006.01); A61B 6/00 (2006.01); A61M 5/14 (2006.01); A61M 5/168 (2006.01); G01T 1/167 (2006.01)
CPC G21G 1/0005 (2013.01) [A61B 6/4057 (2013.01); A61B 6/4258 (2013.01); A61M 5/1408 (2013.01); A61M 5/16827 (2013.01); G01T 1/167 (2013.01); A61M 2205/18 (2013.01); A61M 2205/702 (2013.01)] 32 Claims
OG exemplary drawing
 
1. An infusion system comprising:
a radioisotope generator that generates a radioactive eluate via an elution,
an activity detector configured to measure an activity of a first radioisotope in the radioactive eluate generated by the radioisotope generator; and
a controller configured to:
track a cumulative volume of radioactive eluate generated by the radioisotope generator;
track the activity of the first radioisotope in the radioactive eluate generated by the radioisotope generator; and
determine a predicted volume of the radioactive eluate generated by the radioisotope generator at which the activity of the first radioisotope in the radioactive eluate will reach a threshold based on the tracked cumulative volume of the radioactive eluate and the tracked activity of the first radioisotope.