US 11,808,757 B2
Depth filtration device for separating specimen phases
Kishore K. Bokka Srinivasa Rao, Ridgewood, NJ (US); Daniel J. Marchiarullo, Morris Plains, NJ (US); and Milan Ivosevic, Kinnelon, NJ (US)
Assigned to Becton, Dickinson and Company, Franklin Lakes, NJ (US)
Filed by Becton, Dickinson and Company, Franklin Lakes, NJ (US)
Filed on May 20, 2022, as Appl. No. 17/749,587.
Application 17/749,587 is a continuation of application No. 16/750,165, filed on Jan. 23, 2020, granted, now 11,366,095.
Application 16/750,165 is a continuation of application No. 15/252,804, filed on Aug. 31, 2016, granted, now 10,578,606, issued on Mar. 3, 2020.
Claims priority of provisional application 62/212,797, filed on Sep. 1, 2015.
Prior Publication US 2022/0276221 A1, Sep. 1, 2022
Int. Cl. B01L 3/00 (2006.01); A61B 5/15 (2006.01); G01N 33/49 (2006.01); B01D 15/10 (2006.01)
CPC G01N 33/491 (2013.01) [A61B 5/150022 (2013.01); A61B 5/150343 (2013.01); A61B 5/150358 (2013.01); B01D 15/10 (2013.01); B01L 3/502 (2013.01); B01L 3/5023 (2013.01); B01L 2200/026 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/042 (2013.01); B01L 2300/048 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0838 (2013.01); B01L 2300/123 (2013.01); B01L 2300/14 (2013.01); B01L 2300/161 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/049 (2013.01); B01L 2400/0481 (2013.01)] 7 Claims
OG exemplary drawing
 
1. A device for the collection of a biological sample and separation of the biological sample into a first phase and a second phase, said device comprising:
a collection chamber having an inlet for collecting the biological sample via venous pressure;
a separation chamber fluidically connected to the collection chamber;
a separator located within the separation chamber for separating the biological sample into the first phase and the second phase;
a holder attached to the separation chamber;
a cannula having a first end fluidically connected to the separation chamber and a second end at least partially positioned within the holder; and
a vacuum tube at least partially positioned within the holder, the vacuum tube fluidically connected to the separation chamber via the second end of the cannula, said vacuum tube configured for applying a pressure gradient across the separator to increase a rate of movement of the biological sample through the separator to facilitate separation of the first phase from the second phase and to cause the first phase to enter into the vacuum tube via the cannula.