CPC G01N 30/46 (2013.01) [G01N 30/14 (2013.01); G01N 30/32 (2013.01); G01N 2030/027 (2013.01); G01N 2030/324 (2013.01); G01N 2030/326 (2013.01)] | 16 Claims |
1. A multi-dimensional liquid chromatography system, comprising:
a first liquid chromatography system configured for providing a first chromatographic separation of a sample fluid comprised in a first mobile phase and to provide a first effluent comprising at least a portion of the separated sample fluid,
a second liquid chromatography system configured for providing a second chromatographic separation of at least a portion of the first effluent comprised in a second mobile phase, and
a control unit configured to operate the first liquid chromatography system by maintaining a first flow rate of the first mobile phase substantially constant during the first chromatographic separation, and to operate the second liquid chromatography system during the second chromatographic separation according to a control value different from a second flow rate of the second mobile phase.
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