US 11,808,688 B2
Method and device for detection and/or measurement of impurities in droplets
Denis Kiselev, Perly (CH); and Fabio Capela, Perly (CH)
Assigned to Plair, SA, Perly (CH)
Appl. No. 17/287,697
Filed by Plair SA, Perly (CH)
PCT Filed Oct. 25, 2018, PCT No. PCT/EP2018/079347
§ 371(c)(1), (2) Date Apr. 22, 2021,
PCT Pub. No. WO2020/083500, PCT Pub. Date Apr. 30, 2020.
Prior Publication US 2021/0404942 A1, Dec. 30, 2021
Int. Cl. G01N 15/14 (2006.01); G01N 21/53 (2006.01); G01N 21/64 (2006.01); G01N 21/65 (2006.01); G01N 15/06 (2006.01)
CPC G01N 15/1434 (2013.01) [G01N 15/1459 (2013.01); G01N 21/53 (2013.01); G01N 21/6486 (2013.01); G01N 21/65 (2013.01); G01N 2015/0668 (2013.01); G01N 2015/0693 (2013.01); G01N 2015/1438 (2013.01); G01N 2015/1481 (2013.01); G01N 2015/1486 (2013.01)] 14 Claims
OG exemplary drawing
 
1. Measurement device for the detection and/or measurement of particles in a fluid, the measurement device comprising:
a fluid source configured to produce a flow of fluid along a fluid flow path,
a laser source positioned for emitting a laser beam of laser light in a measurement volume of the fluid flow path;
a first lens set configured to collect a first laser light scattered in the measurement volume by particles contained in the flow of fluid;
a scattered light detecting means configured to detect a presence of a particle in the fluid flow path through detection and measurement of laser beam light scattered on different angles by said particle,
characterized in that it further comprises
a Raman and fluorescence detecting means configured to detect a Raman scattering signal emitted by the fluid and a Fluorescence signal emitted by said particle upon excitation by said laser beam,
wherein said first lens set is configured for focusing the scattered light in a line at a focal distance of the lens set, said line being transverse to a flow direction of the flow of fluid in said measurement volume and wherein said first lens set is configured for focusing said scattered light in a line by focusing said scattered light in a direction parallel to said flow direction and for making the rays of scattered light parallel to each other in a plane perpendicular to said flow direction
further comprising a second lens set for collecting the Raman signal emitted by the fluid molecule and fluorescence signal emitted by the particle upon excitation by said laser beam,
wherein the Raman and fluorescence detecting means is a photo-detector positioned for the detection of laser light collected by the second lens set,
wherein the photo-detector is a linear multipixel detector configured for capturing the laser light focused by the lens set, wherein said linear multipixel detector is positioned at a distance from the focal distance of the lens set and oriented with its longitudinal axis parallel to said line.