Simian adenoviruses SAdV-43, -45, -46, -47, -48, -49, and -50, and uses thereof
Soumitra Roy, Townsend, DE (US); James M. Wilson, Philadelphia, PA (US); and Luc H. Vandenberghe, Weston, MA (US)
Assigned to The Trustees of the University of Pennsylvania, Philadelphia, PA (US)
Filed by The Trustees of The University of Pennsylvania, Philadelphia, PA (US)
Filed on Oct. 29, 2019, as Appl. No. 16/667,608.
Application 16/667,608 is a continuation of application No. 15/449,076, filed on Mar. 3, 2017, granted, now 10,501,757.
Application 15/449,076 is a continuation of application No. 14/548,631, filed on Nov. 20, 2014, granted, now 9,593,346, issued on Mar. 14, 2017.
Application 14/548,631 is a continuation of application No. 13/126,557, granted, now 8,940,290, issued on Jan. 27, 2015, previously published as PCT/US2009/062548, filed on Oct. 29, 2009.
Claims priority of provisional application 61/110,028, filed on Oct. 31, 2008.
Claims priority of provisional application 61/109,986, filed on Oct. 31, 2008.
Claims priority of provisional application 61/109,957, filed on Oct. 31, 2008.
Claims priority of provisional application 61/109,955, filed on Oct. 31, 2008.
Claims priority of provisional application 61/109,958, filed on Oct. 31, 2008.
Claims priority of provisional application 61/109,997, filed on Oct. 31, 2008.
Claims priority of provisional application 61/109,979, filed on Oct. 31, 2008.
Prior Publication US 2020/0263201 A1, Aug. 20, 2020
1. A recombinant adenovirus having an adenovirus capsid comprising a hexon protein, a penton protein, and a fiber protein, wherein said hexon protein is a hexon protein of SAdV-47 comprising amino acids 1 to 958 of SEQ ID NO: 109
said capsid encapsidating a heterologous nucleic acid comprising a gene operably linked to expression control sequences which direct at least one of transcription, translation, and expression of the gene in a host cell.