CPC C07D 491/107 (2013.01) [C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01); C07D 498/18 (2013.01)] | 21 Claims |
1. A compound of the formula:
wherein:
A is a substituted or unsubstituted ring;
R1 is alkyl, alkenyl, alkynyl, alkoxy, aryl, heteroaryl, heterocyclyl, or halo, each of which is independently substituted or unsubstituted; or —C(O)R16, —C(O)OR16, —C(O)NR16R17, —OR16, —SR16, —NR16R17, —NR16C(O)R16, —OC(O)R16, —SiR16R17R18, or hydrogen;
each R3 and R4 is independently alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterocyclyl, each of which is independently substituted or unsubstituted; or —C(O)R19, —C(O)OR19, —C(O)NR19R20, —SOR19, —S02R19, or hydrogen, or R3 and R4 together with the nitrogen atom to which R3 and R4 are bound form a ring, wherein the ring is substituted or unsubstituted;
each R16, R17, and R18 is independently alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterocyclyl, each of which is independently substituted or unsubstituted; or —C(O)R21, —C(O)OR21 —C(O)NR21R22, —OR21, —SR21, —NR21R22, —NR21C(O)R22, —OC(O)R21, hydrogen, or halogen;
each R19 and R20 is independently alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterocyclyl, each of which is independently substituted or unsubstituted; or —C(O)R23, —C(O)OR23, —C(O)NR23R24, —OR23, —SR23, —NR23R24, —NR23C(O)R24, —OC(O)R23, hydrogen, or halogen;
each R21 and R22 is independently alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterocyclyl, each of which is independently substituted or unsubstituted, or hydrogen; and
each R23 and R24 is independently alkyl, alkenyl, alkynyl, aryl, heteroaryl, or heterocyclyl, each of which is independently substituted or unsubstituted, or hydrogen,
or a pharmaceutically-acceptable salt thereof.
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