CPC A61K 9/0056 (2013.01) [A61K 9/7007 (2013.01); A61K 31/4174 (2013.01); A61K 47/34 (2013.01); A61K 47/38 (2013.01); A61P 25/22 (2018.01)] | 15 Claims |
1. A method of treating agitation in a patient comprising administering a film comprising dexmedetomidine or a pharmaceutically acceptable salt thereof, water-soluble hydroxypropyl cellulose polymers having molecular weight of about 40,000 daltons, about 140,000 daltons, and about 370,000 daltons and a water-soluble polyethylene oxide polymer having a molecular weight of about 600,000 daltons, to the oral mucosa of the patient, wherein the method achieves about 70% to about 80% of Cmax within 2 hours of administration, wherein the Cmax is about 78 ng/L to about 200 ng/L, wherein said dexmedetomidine or pharmaceutically acceptable salt thereof is present in the film in an amount of about 40 micrograms.
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