CPC A61K 47/24 (2013.01) [A61K 9/0053 (2013.01); A61K 9/127 (2013.01); A61K 31/137 (2013.01); A61K 31/277 (2013.01); A61K 31/4709 (2013.01); A61K 31/685 (2013.01); A61K 49/0008 (2013.01)] | 5 Claims |
1. A method of treating a drug-induced atrioventricular (AV) block consisting of:
identifying a subject in need of a drug therapy, wherein the drug therapy is contraindicated because it causes a drug-induced atrioventricular (AV) block and the drug therapy consists of a therapeutically effective amount of fingolimod and verapamil that causes AV block; and
providing the subject with the therapeutically effective amount of fingolimod and verapamil, with a single dose of 1 mg/kg of 14:0 lysophosphatidylglycerol sufficient to reduce or eliminate the AV block for at least 1 to 8 hours, wherein the AV block is a third-degree AV block; and
reducing or eliminating the drug-induced AV block by 90, 95, or 100%, wherein the lipid and drug combination are co-administered orally, enterally, parenterally, intravenously, or intraperitoneally.
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