CPC A61K 35/50 (2013.01) [A61K 9/7007 (2013.01); A61P 17/02 (2018.01)] | 14 Claims |
1. A method of preparing a composition for treatment of a wound or lesion in a subject in need thereof, comprising:
(a) contacting an ex-vivo amnion comprising a collagen-containing layer with an amount of a processing agent effective for expanding the collagen-containing layer; and
(b) expanding the collagen-containing layer of the ex-vivo amnion, wherein the expanded collagen-containing layer increases a capacity of the ex-vivo amnion to receive a therapeutic agent for treatment of the wound or lesion in the subject.
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