US 11,806,351 B2
Use of coenzyme factor for activation of ATP production in cell
Tomohisa Nagamatsu, Kumamoto (JP); and Norio Akaike, Kumamoto (JP)
Assigned to TERA STONE Co., Ltd, Kanagawa (JP)
Filed by TERA STONE Co., Ltd, Kanagawa (JP)
Filed on May 6, 2022, as Appl. No. 17/738,027.
Application 17/738,027 is a division of application No. 16/637,280, granted, now 11,439,644, previously published as PCT/JP2019/003860, filed on Feb. 4, 2019.
Claims priority of application No. 2018-018388 (JP), filed on Feb. 5, 2018; and application No. 2019-009224 (JP), filed on Jan. 23, 2019.
Prior Publication US 2022/0265662 A1, Aug. 25, 2022
Int. Cl. A61K 31/519 (2006.01); A61K 31/58 (2006.01); A61P 25/28 (2006.01)
CPC A61K 31/519 (2013.01) [A61K 31/58 (2013.01); A61P 25/28 (2018.01)] 2 Claims
 
1. Use of a deazaflavino-testosterone compound represented by the following formula (III):

OG Complex Work Unit Chemistry
wherein, R1 represents a hydrogen atom, an alkyl group, a halogen-substituted alkyl group, a carboxy-substituted alkyl group, a phenyl group, or a phenyl group substituted by one of a halogen atom, a lower alkyl group, or a lower alkoxy group and R2 represents an alkyl group, a cycloalkyl group, a phenyl-substituted lower alkyl group, a phenyl group, a phenyl group substituted by one of a halogen atom, a lower alkyl group, or a lower alkoxy group, or a lower alkyl disubstituted phenyl group for activating intracellular ATP production,
the use comprising introducing said deazaflavino-testosterone compound to a human-derived neuron cells, wherein said deazaflavino-testosterone compound is used as a coenzyme factor effective for activating intracellular ATP production.