US 11,806,182 B2
Method and apparatus for amyloid screening
Andriy Andreyev, Willoughby Hills, OH (US); Douglas B. McKnight, Chardon, OH (US); Nathan Serafino, Lyndhurst, OH (US); Dane Pittock, Lyndhurst, OH (US); Chuanyong Bai, Solon, OH (US); and Chi-Hua Tung, Aurora, OH (US)
Assigned to KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
Appl. No. 17/270,224
Filed by KONINKLIJKE PHILIPS N.V., Eindhoven (NL)
PCT Filed Aug. 13, 2019, PCT No. PCT/EP2019/071702
§ 371(c)(1), (2) Date Feb. 22, 2021,
PCT Pub. No. WO2020/038773, PCT Pub. Date Feb. 27, 2020.
Claims priority of provisional application 62/720,151, filed on Aug. 21, 2018.
Prior Publication US 2021/0298701 A1, Sep. 30, 2021
Int. Cl. A61B 6/00 (2006.01); G16H 50/30 (2018.01); A61B 6/04 (2006.01)
CPC A61B 6/501 (2013.01) [A61B 6/04 (2013.01); A61B 6/4057 (2013.01); A61B 6/4258 (2013.01); A61B 6/5217 (2013.01); G16H 50/30 (2018.01)] 15 Claims
OG exemplary drawing
 
1. A device for performing an amyloid assessment, the device comprising:
a radiation detector assembly including a plurality of radiation detectors mounted in or on a patient support; and
at least one electronic processor programmed to:
detect radiation counts from the plurality of radiation detectors of the radiation detector assembly over a data acquisition time interval;
compute, from the detected radiation counts, at least one current count metric comprising a total counts detected by the plurality of radiation detectors over the data acquisition time interval, by scaling the at least one current count metric using a predetermined scaling factor based on one or more of patient weight, patient age, patient gender, and patient ethnicity;
store the at least one current count metric associated with a current test date in a non-transitory storage medium; and
determine an amyloid metric based on a comparison of the at least one current count metric with a count metric stored in the non-transitory storage medium associated with an earlier test date.