US 11,806,112 B2
Method, system, software, and device for remote, miniaturized, and three-dimensional imaging and analysis of human lesions research and clinical applications thereof
Joseph Carson, Charleston, SC (US); Sadik Esener, San Diego, CA (US); Kimberly Liu, San Diego, CA (US); David Melnick, Denver, CO (US); and Elyana Crowder, Atlanta, GA (US)
Assigned to Pensievision, Inc., San Diego, CA (US)
Appl. No. 16/304,281
Filed by Pensievision, Inc., San Diego, CA (US)
PCT Filed May 25, 2017, PCT No. PCT/IB2017/000824
§ 371(c)(1), (2) Date Nov. 24, 2018,
PCT Pub. No. WO2017/203369, PCT Pub. Date Nov. 30, 2017.
Claims priority of provisional application 62/341,150, filed on May 25, 2016.
Prior Publication US 2019/0090753 A1, Mar. 28, 2019
Int. Cl. A61B 5/00 (2006.01); A61B 90/00 (2016.01)
CPC A61B 5/0084 (2013.01) [A61B 5/0073 (2013.01); A61B 5/4331 (2013.01); A61B 5/6853 (2013.01); A61B 90/36 (2016.02)] 16 Claims
OG exemplary drawing
 
1. A system for the imaging and analysis of human lesions, comprising:
an illumination component emitting illumination light;
fiber-optic bundles for image capture and illumination, said fiber-optic bundles having a proximal end and a distal end and facilitates the transmission of the emitted illumination light in a direction from the proximal end to the distal end;
an imaging camera at the proximal end of the fiber optic bundles;
an electrically tunable liquid imaging lens connected to the distal end of the fiber-optic bundles in a light transmitting fashion transmitting light to the camera, the electrically tunable liquid imaging lens comprising a transparent, flexible substrate encompassing at least two liquids;
an enclosure, said enclosure housing the electrically tunable liquid imaging lens, illumination component, and the imaging camera; and
a driver accompanying the electrically tunable liquid imaging lens, wherein the driver is configured to control the effective focus of the electrically tunable liquid imaging lens, enabling the imaging camera to capture lesion images within a fraction of a second from each other across a range of focus settings in order to produce a single, sharp, all-focus image.