US 11,791,015 B2
Electrophoresis separation data analyzer
Kota Ogino, Kyoto (JP); Akira Harada, Kyoto (JP); and Hidesato Kumagai, Kyoto (JP)
Assigned to SHIMADZU CORPORATION, Kyoto (JP)
Filed by SHIMADZU CORPORATION, Kyoto (JP)
Filed on Dec. 6, 2019, as Appl. No. 16/705,348.
Claims priority of application No. 2018-244082 (JP), filed on Dec. 27, 2018.
Prior Publication US 2020/0211672 A1, Jul. 2, 2020
Int. Cl. G16B 15/00 (2019.01)
CPC G16B 15/00 (2019.02) 11 Claims
 
1. An analyzer that analyzes separation data obtained by an electrophoresis analysis, the analyzer comprising:
a separation data holding part configured (i) to hold, as reference data, separation data obtained by an electrophoresis analysis of a reference sample including reference components which are known components and (ii) to hold, as testing data to be analyzed, separation data obtained by an electrophoresis analysis of a testing sample to be analyzed;
a determination criterion holding part configured to hold a determination criterion for determining whether component peaks in the reference data and component peaks in the testing data to be analyzed are identical;
a component peak determination part configured to determine whether the component peaks in the reference data and the component peaks in the testing data to be analyzed are identical respectively using the determination criterion; and
an index value designation part configured to require a user to designate, using a separation index value, whether a particular designated component peak of the component peaks in the reference data is or is not present in the testing data to be analyzed,
wherein the component peak determination part is configured to identify that a component peak of the component peaks in the testing data to be analyzed is identical to the particular designated component peak when a difference between the separation index value of the particular designated peak in the reference data and a component-to-be-analyzed index value of the component peak in the testing data to be analyzed satisfies the determination criterion of being identical or not identical;
wherein the analyzer further comprises a waveform correction part configured to normalize the testing data to be analyzed to reduce variation due to a difference in electrophoresis analysis conditions in the testing data to be analyzed by performing a step selected from a waveform correction to expand/contract and/or shift a peak waveform to obtain an analysis target range within a predetermined allowable range so that a correlation between the peak waveform in the analysis target range set in the testing data to be analyzed and the peak waveform in a range in the reference data corresponding to the analysis target range is maximized.