US 11,789,837 B1
Adaptive data collection in clinical trials to increase the likelihood of on-time completion of a trial
Praduman Jain, Fairfax, VA (US); Josh Schilling, Salem, OR (US); and Dave Klein, Oakton, VA (US)
Assigned to VigNet Incorporated, Fairfax, VA (US)
Filed by VigNet Incorporated, Fairfax, VA (US)
Filed on Feb. 3, 2022, as Appl. No. 17/592,440.
Application 17/592,440 is a continuation in part of application No. 17/569,542, filed on Jan. 6, 2022, granted, now 11,645,180.
Application 17/569,542 is a continuation in part of application No. 17/378,643, filed on Jul. 16, 2021, granted, now 11,296,971.
Application 17/378,643 is a continuation in part of application No. 17/324,098, filed on May 18, 2021, granted, now 11,316,941.
Application 17/569,542 is a continuation of application No. 17/233,356, filed on Apr. 16, 2021, granted, now 11,281,553.
Application 17/569,542 is a continuation of application No. 17/592,440.
Application 17/592,440 is a continuation in part of application No. 17/233,103, filed on Apr. 16, 2021, granted, now 11,586,524.
Application 17/233,103 is a continuation in part of application No. 17/185,954, filed on Feb. 25, 2021.
Application 17/378,643 is a continuation in part of application No. 17/177,153, filed on Feb. 16, 2021, granted, now 11,521,714.
Application 17/177,153 is a continuation in part of application No. 17/166,899, filed on Feb. 3, 2021, granted, now 11,196,656, issued on Dec. 7, 2021.
Application 17/166,899 is a continuation in part of application No. 17/166,777, filed on Feb. 3, 2021, granted, now 11,361,846.
Int. Cl. G06F 11/30 (2006.01); G06F 11/34 (2006.01); G06F 18/22 (2023.01); G16H 15/00 (2018.01)
CPC G06F 11/3006 (2013.01) [G06F 11/3075 (2013.01); G06F 11/3438 (2013.01); G06F 18/22 (2023.01); G16H 15/00 (2018.01)] 24 Claims
OG exemplary drawing
 
1. A method performed by one or more computers, the method comprising:
communicating, by one or more computers, with a group of remote devices involved in a research study that involves collection of data from the remote devices over a communication network, each of the remote devices corresponding to a different participant in a cohort of the research study, wherein communicating with the remote devices comprises receiving, from each of the remote devices over the communication network, a series of messages including monitoring data collected by the remote device at different times for one or more types of data specified by the research study;
based on the data collected from the remote devices, determining, by the one or more computers, that an outcome or condition has occurred for a first subset of participants in the cohort during a period of time, wherein the first subset comprises multiple participants in the cohort, and wherein the cohort includes a second subset of participants for which the outcome or condition was not detected to occur during the period of time; and
based on determining that the outcome or condition has occurred for the first subset of participants:
generating, by the one or more computers, parameters to adapt monitoring performed for participants in the cohort, wherein the parameters change a procedure for collecting the one or more types of data or add an additional type of data to collect from participants in the cohort; and
configuring, by the one or more computers, the remote devices of at least some of the participants in the cohort to perform adapted monitoring according to the generated parameters, such that (i) the remote devices of the participants in the first subset and the second subset are configured to perform the adapted monitoring and (ii) acquired data generated using the adapted monitoring is provided to a server over the communication network.